40 Factors That Increase Your Risk of Heart Disease After 40

It's time to scale back on these habits leaving you at risk of heart disease in your 40s and beyond.

middle aged man holds heart while outside

Heart disease is the number one killer of both men and women worldwide. According to the Centers for Disease Control and Prevention (CDC), approximately 647,000 individuals die from the condition in the United States alone each year—meaning heart disease accounts for one in every four deaths stateside. And unfortunately, while some things get better with age, your heart health is not typically one them. According to 2013 data from the American Heart Association, 6 percent of men and 5.5 percent of women between the ages of 40 and 59 have coronary heart disease (CHD). And among those 60 to 79 years old, those numbers at least double: 21.1 percent of men and 10.6 percent of women in that age bracket have CHD. If you want to avoid becoming a statistic, there's still plenty of time to consider the factors that increase your risk of heart disease after 40. Make changes today, so that you can have many healthy years to look forward to!

Living at a low altitude

panama city beach florida

If you have a choice between living at the beach or in the mountains in your 40s, choose the latter—your heart will thank you. According to a 2017 study published in the journal Frontiers in Physiology, lower-altitude living is associated with a greater risk of metabolic syndrome, which can contribute to heart disease.

Not flossing

Closeup of woman's hand holding dental floss

Your oral health and your heart health are more connected than you think. According to a 2016 study published in the BMJ Postgraduate Medical Journal, oral bacteria can contribute to a person's risk of atherosclerosis, or hardening and narrowing of the arteries, which can significantly increase the likelihood of heart disease.

Skipping breakfast

heart attack after 40

Starting the day off right with a healthy breakfast could ultimately save your life. A review of research published in the journal Circulation in 2013 found a significant link between eating breakfast and a reduced risk of coronary heart disease.

Having more than one or two drinks a day

people drinking

A glass of red wine once in a while might have some heart health benefits, but regular drinking can put you at risk of heart disease. "Too much alcohol can increase blood pressure and triglycerides, which can increase your risk of heart disease," says Sarin Seema, MD, of EHE Health. Her recommendation? "Women should have no more than one drink a day. Men should have no more than two drinks a day."

Social isolation

Woman looking sad and unmotivated on the couch

Having friends is not only important to your happiness, but the friendships you make may actually help your heart in the long run. According to a 2016 study published in the journal Heart, social isolation can significantly increase a person's risk of developing heart disease. Those who reported poor social relationships had a 29 percent greater chance of having coronary heart disease than those with healthier ones.

Working nights

tired doctor or nurse working the night shift, school nurse secrets

Want a healthier heart? Try switching from the night shift to a nine to five schedule, if possible. Research published in the Journal of the American Medical Association (JAMA) in 2016 discovered a link between long-duration night-shift work and an increased risk of coronary heart disease.

Commuting by car

Man in car

If you want to reduce your risk of heart disease, consider commuting by bike whenever possible. Research published in the journal Archives of Internal Medicine in 2009 proved that individuals who commuted to work by bike or foot had lower rates of obesity and thusly, reduced their risk of heart disease.

Sitting all day

woman sitting at a desk in front of a laptop, ways to feel amazing

There's no time like the present to spring for a treadmill desk if you're eager to improve your heart health. A 2012 study published in the journal Diabetology found that a sedentary job increased an individual's risk of developing heart disease by 147 percent.

Having a difficult boss

An angry, upset boss running a meeting.

The dynamic of having an overbearing boss who's always on your back for one thing or another might be doing more than just leaving you frustrated and irritable at the end of the day. The results of a 2009 Swedish study published in the journal Occupational and Environmental Medicine found that people with uncommunicative, secretive, inconsiderate, and incompetent bosses increased their risk of having a severe cardiovascular event by 60 percent.

Sleeping too much

middle aged latino man sleeping on his stomach

While skimping on sleep is bad for your wellbeing, getting too much sleep can actually be worse for your heart health than not getting enough. A meta-analysis of research published in the Journal of the American Heart Association in 2018 revealed that getting more than eight hours of sleep can significantly increase a person's risk of cardiovascular disease (CVD), with a moderate risk for those who got nine hours of sleep and nearly a 44 percent increase among those logging 11 hours a night.

Giving birth

mom holding newborn baby at the hospital

Having kids isn't just hard on your wallet and schedule—it can be hard on your heart, too. A review of data published in the European Journal of Preventive Cardiology in 2018 revealed that the more times a person gives birth, the greater their risk of heart disease is.

Not spending enough time outside

Man Reading Poems to Woman

A little green space can do your heart a world of good. A review of research published in Current Epidemiology Reports in 2015 found that exposure to nature not only improves mental health, but it can also improve a person's cardiovascular health. According to the researchers, "higher levels of greenness were associated with lower risk of CVD, ischemic heart disease, and stroke mortality."

Catching the flu

sick white man in bed with tissues

Getting the flu will do more than just eat up your sick days—it could contribute to your risk of potentially fatal cardiovascular disease. According to a 2018 study published in The New England Journal of Medicine, within the first seven days of a confirmed flu diagnosis, patients have a significantly increased risk of heart attack.

Not having sex regularly

couple wearing pajamas in bed flipping through channels on the television - how often do couples have sex

Time to cue up the Marvin Gaye and break out a good bottle of wine—for your heart health, of course. As it turns out, not having regular sex could be contributing to your heart disease risk. A review of research published in the American Journal of Cardiology in 2010 found that having sex one time a month or less increased a person's risk of cardiovascular disease.

Not controlling your diabetes

man getting a diabetes test at the doctors office

If you're over 40, it's time to make sure you're monitoring your blood sugar, especially if you have a family history of diabetes or risk factors like obesity, high blood pressure, or a sedentary lifestyle.

"Sugars build up in the blood and increase your risk of heart disease," says Seema. Her suggestion to mitigate this risk? "Having a healthy diet, exercising regularly, eating whole food plant-based nutrition can all help to lower your blood sugar levels."

Undergoing breast cancer treatment

heart attack after 40

According to the American Heart Association, there's a link between the treatments for breast cancer, like chemotherapy, and an increased risk of cardiovascular disease. However, there are numerous ways to slash your risk of developing either disease, like losing weight and quitting smoking.

Not exercising at all

white couple texting on couch
Shutterstock/Tero Vesalainen

Skipping the gym one too many times could be a big problem for your heart down the road. "Physical inactivity is a risk factor for heart disease," says Seema. "Not only does [exercising] help with achieving a normal body mass index (BMI), blood pressure, cholesterol, and blood sugar levels, [it] can also help with stress management."

So, how much time should you be spending at the gym? Thirty minutes of moderate activity a day, or 150 minutes a week, will reduce your heart disease risk.

Or exercising too intensely

close up of black man sweating while doing a stretch at the gym

However, that doesn't mean you should overdo it to the point of exhaustion or pain. Because if you do, your heart could also pay the price.

"Lasting stress on the heart can lead to something called 'athletic heart syndrome,'" says clinical nutritionist and fitness expert Ariane Hundt, MS. "Your heart becomes enlarged in order to keep up with the stress placed on it. It can also lead to an increase in your body's stress response (high cortisol and adrenaline) and result in irregular heartbeat."

Dealing with chronic stress

Portrait of black man with hand covering face and thinking. Male in checkered shirt looking worried on black background.

From bad relationships to long hours at work, your daily stressors could have serious implications in terms of your heart health. "Stress that goes unmanaged and lasts for extended periods results in increased cortisol levels and leads to an inflamed system," Hundt says. She adds that "long-term stress suppresses the immune system and allows [heart] disease to occur."

Getting angry

Side view image of irritated man shouting at other drivers while driving on the highway

We've all been guilty of losing our temper from time to time, but it's in the best interest of your heart to try to manage how often you're losing your cool. Regular feelings of anger have been linked to an increased risk of heart attack, according to a 2015 study published in the European Heart Journal. The researchers behind the study found that episodes of intense anger were directly linked to a greater risk of acute heart occlusion, which obstructs blood flow to the heart.

Not treating your depression

Man with beard holding his chin, standing beside a window at night

Addressing your depressive symptoms is the first step toward a healthier heart. According to research published in Psychosomatic Medicine in 2014, early treatment for depression can cut a person's risk of cardiovascular disease in half. So if you're feeling blue, there's no time like the present to improve your mental health.

Not drinking enough water

A senior African American Man enjoying refreshing water after a workout

If you're not sipping water throughout the day, you could be setting yourself up for heart problems after 40. Research published in a 2017 issue of the European Journal of Nutrition found that even minor dehydration can increase a person's risk of cardiovascular disease.

Having high blood pressure


If your last blood pressure reading was higher than normal, do everything in your power to decrease those numbers—or you could be staring down heart disease in the future.

"A healthy diet, reducing stress, decreasing salt intake, and exercising regularly can reduce your blood pressure," according to Seema. In turn, you'll also decrease your risk of heart disease.

Or having high cholesterol

blueshot / iStock

Ignoring high cholesterol levels now may mean setting yourself up for serious heart trouble down the line. According to family and emergency medicine doctor Janette Nesheiwat, MD, high cholesterol is one of the biggest contributing factors to your risk of heart disease.


american words offensive in other countries

"If you smoke, quit now," says David Greuner, MD, of NYC Surgical Associates. Smoking significantly increases an individual's risk of heart disease, as well as their risk of high blood pressure, diabetes, and stroke.

Or using nicotine patches or gum to quit smoking

Nicotine patch on woman's arm

And if you're trying to quit smoking, make sure you're not using nicotine-based smoking cessation products longer than necessary. "Nicotine raises blood pressure, which is another risk factor for heart disease," says Seema.

Drinking too much caffeine

People hands holding cups of coffee

A cup of coffee from time to time likely won't hurt you, but over-reliance on caffeine can increase your heart disease risk.

"Excessive caffeine consumption … contributes to stress in the body," which can lead to increased risk of heart disease, according to Hundt.

Drinking diet soda

black woman having lunch with family in the kitchen at home, drinking diet soda and eating salad

Think opting for diet soda instead of the sugary regular version is the more healthy choice for your heart? Think again. According to 2012 research published in the Journal of General Internal Medicine, even among individuals without other risk factors, regular consumption of diet drinks increases your risk of heart disease.

Eating blackened food

Blackened catfish and rice plate

Cooking your food thoroughly is essential to prevent food poisoning, but blackening your meat or fish—a popular, and delicious, barbecue technique—isn't doing your heart any favors.

"Eating a diet high in inflammatory foods is a big risk factor," says Hundt. "Fatty cuts of meat that are grilled until they're charcoal increases [cardiovascular disease] risk."

Eating tons of fried food

fried chicken sandwich on a white plate, trademark failures

You may have been able to get away with fried food at 20, but at 40, those greasy snacks are not making your heart happy. Even eating fried chicken just once a week increased a person's risk of heart disease by 12 percent, according to a 2019 study published in the British Medical Journal.

Eating too much sugar

woman eating chocolate cake with a fork

If you want to decrease your risk of heart disease, start by weaning yourself off the sugar in your diet. "Eating a diet high in sugar and processed foods increases insulin and in turn inflammation, which creates damage to the arteries," says Hundt. "The resulting increase in cholesterol is then used to patch up the arterial damage. Over time, this buildup of plaque leads to a narrowing of the arteries," contributing to your risk of heart disease.

Consuming too much saturated fat

hamburger and french fries

If you want to lower your risk of heart disease, reducing your consumption of animal products in favor of fruits, vegetables, and plant-based proteins is a great place to start. "Saturated fats, trans fats, and cholesterol can contribute to heart disease," says Seema. "Eating a plant-based, whole food diet has been shown to decrease the risk of heart disease in many studies. It also helps lower your cholesterol and LDL levels, which decreases your risk of heart disease, as well."

Not getting enough fiber

A healthy, high fiber oats and berries breakfast

Those regular refined carbohydrates and steak dinners are likely hurting your heart. If you want to avoid developing heart disease after 40, "eat a well-balanced, high-fiber diet," says Nesheiwat.

Not getting enough omega-3 fatty acids

omega 3 fish oil supplements

"A lack of omega-3 fatty acids is a major contributor to heart disease," according to Hundt. The key nutrients provided by fish oils can be incorporated into your diet by consuming certain types of seafood, or in dietary supplements you can buy at any drug store. However you consume them is your choice, but just make sure you are getting enough of the fatty acids in your diet.

Or getting far too much omega-6 fatty acids

ear of corn, funniest jokes

Like omega-3, omega-6 is a fatty acid, but generally speaking, people consume much more of it than they should, throwing off what should be a healthy balance of the two essential acids.

"It is important to have a healthy balance between omega-6 and omega-3 fatty acids," says Jessica Wilhelm, CN, clinical team director of Wellnicity. "The ratio between omega-6 and omega-3 should be between 4:1 and 2:1. However, the standard American diet contains up to a 20:1 ratio, meaning we consume up to 20 times more omega-6s than omega-3s."

To know what you should steer clear of for the sake of your heart health, omega-6 fatty acids are found in things like corn and vegetable oil.

Not getting enough magnesium

higher energy person

"Magnesium is a mineral involved in over 300 different metabolic processes in the body that are critical for cardiac health," says Wilhelm. "Having adequate levels of magnesium is associated with a lower risk for cardiovascular disease, but can also support healthy blood pressure because of its smooth muscle relaxing properties."

So, how do you know if you're deficient? "Anxiety, fatigue, muscle cramps, stiffness, and twitching are all signs that you're not getting enough magnesium in your diet," according to Wilhelm.

Taking medicines that deplete your CoQ10 levels

pills spilling out of a container

CoQ10 acts as an antioxidant that plays an important part in your metabolism. But, according to Wilhelm, "depletion of this heart-healthy nutrient can occur when taking blood pressure medications classified as beta blockers and statin medication to lower cholesterol."

Fortunately, supplementation and eating foods like fatty fish, oranges, strawberries, lentils, peanuts, spinach, cauliflower, and broccoli can increase your levels of this important nutrient that keeps your heart free of disease.

Ignoring your family history

woman at the doctor

Your family history shapes who you are, including your risk of heart disease. According to research published in the journal Circulation in 2012, men with a family history of heart disease had about a 50 percent increased risk of developing cardiovascular issues themselves. Luckily, having this information and controlling other risk factors, like diet and activity level, can help you live a longer, healthier life.

Being overweight

Overweight woman touching pain in leg

There's no time like the present to lose those extra pounds, especially if you're already at a higher risk of cardiovascular disease than normal. "Obesity is linked to heart disease, a higher LDL, triglycerides, and lower HDL, which are all risk factors for heart disease," says Seema.

Getting divorced

woman taking off wedding ring

While bailing on a lackluster marriage may be good for you in the long run, the stress brought on by getting a divorce after 40 could increase your risk of heart disease, according to a 2017 study published in the journal Cardiology Research and Practice. The study revealed that women who had gone through a divorce ran an increased risk of serious heart conditions. If they went through multiple divorces, the increase in their risk of heart disease became even more significant. (Curiously, the same connection between divorce and heart disease was not found in men, the study determined.)

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